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3-O-Methyldopa-d3 (3-OMD-d3)

目录号 数量 价格 提前通知时间
4995-1mg 1.0 mg $228 12 天
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3-O-Methyldopa-d3 (3-OMD isotopic standart), 3-Methoxy-L-tyrosine, is a metabolite of L-dioxyphenylalanine (DOPA, L-DOPA, the drug levadopa), which is formed by the action of catechol-O-methyltransferase (COMT). 3-Methoxy-L-tyrosine competitively inhibits the pharmacodynamics of L-DOPA and dopamine. 3-Methoxy-L-tyrosine is an important marker for screening Parkinson's disease patients taking the drug levadopa. 3-Methoxy-L-tyrosine is also a major biochemical marker of aromatic L-amino acid decarboxylase deficiency (AADC, EC 4.1.1.28), an inborn error of metabolism that affects serotonin and dopamine biosynthesis.

General properties

Appearance: white powder
Molecular weight: 250.69
CAS number: 586954-09-8
Molecular formula: C10H11D3ClNO4
Solubility: water
Quality control: NMR 1H and HPLC-MS (95+ %, D: 98+ %)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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