生物结合试剂

生物结合试剂 / 产品分类和该类别中的产品
Bioconjugation reagents: biotin, streptavidin, biotinylation reagents, bifunctional cross-linkers, PEG-linkers, auxiliary reagents for click chemistry, etc.

活化酯

Bifunctional activated NHS and STP esters for binding with primary and secondary amine groups.
群组标签 交联, 蛋白质标记, NHS酯类, NHS酯类, 环烯烃, 无铜点击化学, 生物素化, 环炔烃, 炔烃, 马来酰亚胺, 点击化学, 叠氮化物

叠氮化物

Various non-fluorescent azides for click chemistry. Fluorescent azides are listed under Reactive dyes category.
群组标签 酰肼类, 交联, 蛋白水解靶向嵌合体(PROTAC), 蛋白质标记, NHS酯类, 无铜点击化学, 四嗪类, 生物素化, 胺类, 马来酰亚胺, 羧酸, 点击化学, 卤化物, 叠氮化物

炔烃

Various terminal alkynes for сlick сhemistry. Fluorescent dye alkynes are listed under 'Reactive dyes' category.
群组标签 酰肼类, 交联, 酪酰胺, 蛋白质标记, NHS酯类, NHS酯类, 生物素化, 胺类, 炔烃, 马来酰亚胺, 羧酸, 点击化学, 卤化物

环炔烃

Highly reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition).
群组标签 交联, 蛋白质标记, NHS酯类, NHS酯类, 无铜点击化学, 环炔烃, 胺类, 马来酰亚胺
    • DBCO-NHS 酯
      偶氮二苯并环辛炔 (DBCO、ADIBO) 试剂用于应变促进的无铜点击化学 (SPAAC)。该试剂含有 NHS 酯官能团，用于将环辛炔连接到各种分子上。
    • DBCO-STP酯 (DBCO-STP ester)
      一种活化酯用于蛋白质/抗体/肽的修饰，引入到无铜点击化学反应。
    • DBCO-amine trifluoroacetate
      Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.
    • DBCO-PEG6-NHS ester
      A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).
    • exo-BCN-PNP
      BCN-PNP 碳酸酯是一种通过氨基甲酸酯与底物伯氨基连接引入 BCN 基团的工具。
    • DBCO-马来酰亚胺 (DBCO-maleimide)
      双功能连接体含有硫醇反应性马来酰亚胺基团和叠氮化物反应性二苯并环辛炔部分。

四嗪

Non-fluorescent tetrazines for inverse electron demand Diels-Alder reaction (IEDDA) with terminal alkenes and strained olefins, such as trans-cyclooctenes and some cyclooctynes.
群组标签 交联, 无铜点击化学, 四嗪类, 生物素化, 点击化学, 叠氮化物
    • Tetrazine-PEG3-OH
      Tetrazine-PEG3-OH is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.
    • Azide-PEG3-tetrazine
      A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
    • Biotin-PEG4-tetrazine
      Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.

环烯烃

Cycloalkenes for copper-free alkene-tetrazine click reaction.
群组标签 交联, 蛋白质标记, NHS酯类, 环烯烃, 无铜点击化学

胺类

Amines for the coupling with various electrophilic compounds like activated esters and epoxides.
群组标签 交联, 蛋白水解靶向嵌合体(PROTAC), 无铜点击化学, 生物素化, 环炔烃, 胺类, 炔烃, 羧酸, 点击化学, 叠氮化物

酰肼

Hydrazides are carbonyl-reactive reagents for the labeling of aldehydes and ketones.
群组标签 酰肼类, 交联, 蛋白质标记, 生物素化, 炔烃, 点击化学, 叠氮化物
    • 炔酰肼 (Alkyne hydrazide)
      含有炔基和酰肼官能团的双功能试剂。它与醛和酮发生反应。然后炔基可以通过 CuAAC 反应与各种叠氮化物偶联。
    • Biotin-X-hydrazide
      Hydrazide biotin reagent with aminocaproic spacer useful for biotinylation of macromolecule reactive carbonyls.
    • 叠氮-PEG4-酰肼 (Azide-PEG4-hydrazide)
      含有叠氮基团和酰肼官能团的双功能试剂。它与醛和酮发生反应。叠氮基团可以通过 CuAAC 反应与各种炔烃偶联。

马来酰亚胺

Maleimides are thiol-reactive compounds for labeling sulfhydryl (thiol) groups in proteins.
群组标签 交联, NHS酯类, 无铜点击化学, 生物素化, 环炔烃, 炔烃, 马来酰亚胺, 点击化学, 叠氮化物

硫醇类

Bifunctional reagents with a thiol (-SH) functional group. Thiols are nucleophilic compounds that participate in many reactions with electrophiles.
群组标签 交联, 硫醇
    • Hydroxy-PEG3-thiol
      PEG3 bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
    • Hydroxy-PEG2-thiol
      Short bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.

卤化物

Halogen derivatives with reactive groups for bioconjugation.
群组标签 交联, 生物素化, 炔烃, 羧酸, 点击化学, 卤化物, 叠氮化物
    • Iodo-PEG3-carboxylic acid
      A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.
    • Azide-PEG3-chloride
      Azide-PEG3-chloride contains a reactive halogen atom and an azide group for click chemistry reaction. It can also serve as a protected amine group equivalent.
    • Iodo-PEG3-iodide
      Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.
    • 炔基-PEG2-碘化物 (Alkyne-PEG2-iodide)
      含有末端炔基（可用于点击化学或 Sonogashira 偶联反应）和活性烷基碘基团的双功能交联剂。
    • Azide-PEG3-iodide
      Azide-PEG3-iodide is a bifunctional linker with a highly reactive alkylative halogen functional group and an azido group for click chemistry or Staudinger ligation.
    • Alkyne-PEG3-iodide
      PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
    • Alkyne-PEG4-iodide
      Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
    • Azide-PEG2-iodide
      A bifunctional molecule containing hydrophilic PEG2 with azide and iodide groups.
    • Biotin-PEG4-iodide
      A highly reactive biotinylation reagent that readily and efficiently interacts with various nucleophiles.

羧酸

Carboxylic acids with reactive groups for the conjugation of different biomolecules.
群组标签 交联, 蛋白水解靶向嵌合体(PROTAC), 生物素化, 胺类, 炔烃, 羧酸, 点击化学, 卤化物, 叠氮化物

酒精类

Alcohols with reactive groups for the conjugation of different biomolecules.
群组标签 交联, 蛋白水解靶向嵌合体(PROTAC), 硫醇, 无铜点击化学, 四嗪类, 生物素化, 胺类, 炔烃, 点击化学, 叠氮化物
    • Alkyne-PEG3-OH
      Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
    • Tetrazine-PEG3-OH
      Tetrazine-PEG3-OH is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.
    • Azide-PEG3-OH
      Azide-PEG3-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG3 linker in between.
    • Hydroxy-PEG3-thiol
      PEG3 bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
    • Hydroxy-PEG2-thiol
      Short bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
    • Azide-PEG4-OH
      Azide-PEG4-OH is a bifunctional molecule with an azide group, primary alcohol, and a hydrophilic PEG4 linker in between.
    • 胺-PEG4-OH (Amine-PEG4-OH)
      一种具有末端氨基和羟基的亲水性四甘醇衍生物。
    • 3-Azidopropanol
      Azidopropanol is a short bifunctional linker compound with azide and hydroxyl functional groups.
    • Amine-PEG3-OH
      Bifunctional PEG3 derivative with amine and hydroxyl groups.
    • 叠氮化物-PEG6-OH (Azide-PEG6-OH)
      水溶性异质双功能交联剂，具有伯羟基、炔反应性叠氮基和 PEG6 亲水连接基。
    • 氨基-PEG6-醇 (Amine-PEG6-OH)
      具有末端氨基和羟基的亲水性六乙二醇衍生物。
    • 生物素-PEG3-OH (Biotin-PEG3-OH)
      具有生物素和羟基的双功能三乙二醇连接子。

生物素

Biotin derivatives with different spacers for introducing biotin labels into proteins, antibodies, and nucleic acids.
群组标签 酰肼类, 交联, 显微镜观察, 酪酰胺, 蛋白质标记, NHS酯类, 无铜点击化学, 四嗪类, 生物素化, 胺类, 炔烃, 磺基青光素5 (sulfo-Cyanine5), 马来酰亚胺, 羧酸, 点击化学, 神经科学, 卤化物, 叠氮化物, 磺基-花菁3

同型双功能试剂

Homobifunctional crosslinkers with identical reactive groups at opposite ends of the spacer for intramolecular crosslinks and chemical crosslinking of macromolecular chains.
群组标签 交联, NHS酯类, 羧酸, 点击化学, 卤化物, 叠氮化物

点击化学配体和催化剂

Auxiliary reagents for click chemistry: catalysts, buffers, and ligands for copper-catalyzed click reaction (CuAAC).
群组标签 点击化学

生物结合辅助试剂

Auxiliary reagents, various buffers, and solvents for labeling and conjugation.
群组标签 点击化学
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