生物结合试剂

生物结合试剂 / 产品分类和该类别中的产品
Bioconjugation reagents: biotin, streptavidin, biotinylation reagents, bifunctional cross-linkers, PEG-linkers, auxiliary reagents for click chemistry, etc.

活化酯（双官能团）

Bifunctional activated NHS and STP esters for binding with primary and secondary amine groups.
群组标签 Crosslinking, NHS esters, Cycloalkenes, Copper-free click chemistry, STP esters, Biotinylation, Cycloalkynes, Maleimides, Azides, Alkynes, Click chemistry, Protein labeling

炔烃

Various terminal alkynes for сlick сhemistry. Fluorescent dye alkynes are listed under 'Reactive dyes' category.
群组标签 Crosslinking, NHS esters, STP esters, Biotinylation, Maleimides, Carboxylic acids, Alkynes, Halides, Hydrazides, Click chemistry, Protein labeling, Amines
  • Alkyne-PEG2-NHS ester
    Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on diethyleneglycol (PEG2).
  • Alkyne-PEG2-amine
    Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
  • Alkyne-PEG2-carboxylic acid
    Bifunctional diethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
  • Alkyne-PEG2-iodide
    Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
  • Alkyne-PEG3-NHS ester
    Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).
  • Alkyne-PEG3-OH
    Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.
  • Alkyne-PEG3-amine
    Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
  • Alkyne-PEG3-carboxylic acid
    Bifunctional triethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
  • Alkyne-PEG3-iodide
    PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
  • Alkyne-PEG4-NHS ester
    Bifunctional hydrophilic linker with NHS ester and terminal alkyne functional group based on tetraethyleneglycol (PEG4).
  • Alkyne-PEG4-amine
    A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
  • Alkyne-PEG4-carboxylic acid
    Bifunctional tetraethyleneglycol linker with terminal alkyne and carboxylic acid moieties.
  • Alkyne-PEG4-iodide
    Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
  • Alkyne-PEG4-maleimide
    Water soluble, heterobifunctional hydrophilic linker with a length of 14 Å, containing maleimide for thiol labeling, and alkyne for click chemistry. An ideal reagent to attach an alkyne moiety to a protein.
  • Biotin-PEG2-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Biotin-PEG4-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Hexynoic acid STP ester
    Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.
  • 己酸NHS酯 (Hexynoic acid NHS ester)
    己酸 NHS 酯，用于铜催化点击化学中带有炔基的生物分子标记。
  • 戊烯酸STP酯 (Pentynoic acid STP ester)
    一种活化酯，用于将炔基引入肽/蛋白质和链接反应。
  • 炔基马来酰亚胺 (Alkyne maleimide)
    马来酰亚胺试剂用于将炔基官能团连接到蛋白质、多肽和其它含有 SH（硫醇）基团的分子上，包括半胱氨酸残基。
  • 炔烃-PEG3-马来酰亚胺
    具有炔基和马来酰亚胺基团的双功能间隔基。
  • 炔酰肼 (Alkyne hydrazide)
    含有炔基和酰肼官能团的双功能试剂。它与醛和酮发生反应。然后炔基可以通过 CuAAC 反应与各种叠氮化物偶联。

环烯烃

Cycloalkenes for copper-free alkene-tetrazine click reaction.
群组标签 NHS esters, Cycloalkenes, Copper-free click chemistry, Protein labeling

胺类

Amines for the coupling with various electrophilic compounds like activated esters and epoxides.
群组标签 Crosslinking, PROTAC, Copper-free click chemistry, Biotinylation, Cycloalkynes, Carboxylic acids, Azides, Alkynes, Click chemistry, Amines
  • (S,R,S)-AHPC-PEG2-C2-amine
    Degrader building block containing an E3 ligase ligand with linker and amino group for conjugation with other functionalized linkers and target protein ligands.
  • 3-Azidopropylamine hydrochloride
    A bifunctional short linker with amino and azido groups. A solid, chemically stable hydrochloride form of azidopropylamine. This product is ideal as an azidopropylamine bulk for applications when a large amount of reagent is needed.
  • Alkyne-PEG2-amine
    Diethyleneglycol (PEG2) based bifunctional linker containing amine and alkyne functional groups.
  • Alkyne-PEG3-amine
    Alkyne-PEG3-amine is a medium-length heterobifunctional linker for conjugation.
  • Alkyne-PEG4-amine
    A bifunctional linker molecule containing both terminal alkyne moiety for click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.
  • Amine-PEG2-carboxylic acid
    Hydrophilic PEG2-linker with a terminal amino group and a carboxyl group.
  • Amine-PEG3-OH
    Bifunctional PEG3 derivative with amine and hydroxyl groups.
  • Amine-PEG3-carboxylic acid
    Hydrophilic PEG3-linker with a terminal amino group and a carboxyl group.
  • Azide-PEG2-amine
    A diethylene glycol (PEG2) linker with azide and amino groups.
  • Azide-PEG3-amine
    A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)
  • Azide-PEG4-amine
    PEG4 amine azide is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.
  • Biotin-PEG2-amine
    Diethylene glycol (PEG2) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG3-amine
    Triethylene glycol (PEG3) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG4-amine
    Tetraethylene glycol (PEG4) based bifunctional molecule containing biotin and amine functional group.
  • DBCO-amine trifluoroacetate
    Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.
  • Thalidomide-O-PEG2-amine
    Thalidomide-containing building block with PEG2-linker and amino group for conjugation with other functionalized linkers and target protein ligands.
  • VHL Ligand 1 dihydrochloride
    VHL Ligand 1 is a building block for synthesizing proteolysis-targeting chimera (PROTAC) molecules.
  • 氨基-PEG6-醇 (Amine-PEG6-OH)
    具有末端氨基和羟基的亲水性六乙二醇衍生物。
  • 盐酸四甘氨酸 (Tetraglycine hydrochloride)
    四甘氨酸是由4个甘氨酸单体组成的寡肽。基于氨基和羧基，它被用作双功能接头。
  • 胺-PEG4-OH (Amine-PEG4-OH)
    一种具有末端氨基和羟基的亲水性四甘醇衍生物。
  • 胺-PEG4-羧酸 (Amine-PEG4-carboxylic acid)
    具有末端氨基和羧基的亲水性 PEG4 连接体。

叠氮化物

Various non-fluorescent azides for click chemistry. Fluorescent azides are listed under Reactive dyes category.
群组标签 Crosslinking, PROTAC, NHS esters, Copper-free click chemistry, Tetrazines, Biotinylation, Maleimides, Carboxylic acids, Azides, Halides, Click chemistry, Protein labeling, Amines

生物素和链霉亲和素

Biotin derivatives with different spacers for introducing biotin labels into proteins, antibodies, and nucleic acids. Fluorescent dye conjugates of biotin and streptavidin.
群组标签 AF 488, Crosslinking, NHS esters, Copper-free click chemistry, Tetrazines, Biotinylation, AF 594, Maleimides, Carboxylic acids, Neuroscience, Azides, Flow cytometry, Alkynes, Halides, Hydrazides, sulfo-Cyanine3, Microscopy, Click chemistry, Super-resolution imaging, sulfo-Cyanine5, Protein labeling, Amines, AMCA
  • AF 488 streptavidin
    AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AF 594 streptavidin
    AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AMCA链霉亲和素 (AMCA streptavidin )
    一种链霉亲和素的 AMCA 偶联物（高亲和力生物素结合蛋白），用于免疫荧光、蛋白质印迹、微孔板测定和其他应用。
  • Biocytin hydrochloride
    Lysine derivative of biotin for conjugation with avidin or streptavidin, neuroanatomical tracer.
  • Biotin-PEG2-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Biotin-PEG2-azide
    Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • Biotin-PEG3-amine
    Triethylene glycol (PEG3) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG4-NHS ester
    PEG4-containing activated ester for simple and efficient biotin labeling of antibodies, proteins, and other primary amine-containing biomolecules.
  • Biotin-PEG4-alkyne
    Biotin alkyne is a reagent for click chemistry labeling with biotin, an affinity probe to streptavidin.
  • Biotin-PEG4-amine
    Tetraethylene glycol (PEG4) based bifunctional molecule containing biotin and amine functional group.
  • Biotin-PEG4-azide
    Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • Biotin-PEG4-carboxylic acid
    Bifunctional tetraethyleneglycol linker with biotin and carboxylic acid moieties.
  • Biotin-PEG4-iodide
    A highly reactive biotinylation reagent that readily and efficiently interacts with various nucleophiles.
  • Biotin-PEG4-tetrazine
    Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • Biotin-X-NHS ester
    Biotin derivative with C6-spacer to reduce steric effect when binding amino acids, peptides, or proteins by reacting with primary amines.
  • Biotin-X-hydrazide
    Hydrazide biotin reagent with aminocaproic spacer useful for biotinylation of macromolecule reactive carbonyls.
  • Biotin-cystamine hydrochloride
    Biotin and cystamine conjugate is a cleavable biotinylation reagent.
  • sulfo-Cyanine3 streptavidin
    sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • sulfo-Cyanine3-PEG3-biotin
    Conjugate of hydrophilic sulfo-Cyanine3 dye with biotin, affinity label for avidin/streptavidin.
  • sulfo-Cyanine5-PEG3-biotin
    Biotin conjugate of the far-red fluorescent sulfo-Cyanine5 dye.
  • sulfo-Cyanine5链霉亲和素 (sulfo-Cyanine5 streptavidin)
    链霉亲和素的sulfo-Cyanine5 偶联物，是一种高亲和力的生物素结合蛋白，用于免疫荧光、蛋白质印迹、酶标仪和其他应用。
  • 生物素 X 马来酰亚胺 (Biotin-X-maleimide)
    硫醇反应性双功能连接子，用于将生物素连接到蛋白质、多肽和其他巯基化分子上。
  • 生物素-PEG3-OH (Biotin-PEG3-OH)
    具有生物素和羟基的双功能三乙二醇连接子。
  • 生物素-PEG3-叠氮化物 (Biotin-PEG3-azide)
    生物素叠氮化物是一种用生物素进行点击化学标记的试剂，生物素是一种著名的链霉亲和素亲和探针。
  • 生物素-XX-NHS酯 (Biotin-XX-NHS ester)
    生物素衍生物，长的间隔基可减少空间效应，可通过与伯胺反应与氨基酸、肽或蛋白质结合。
  • 生物素炔 (Biotin alkyne)
    生物素炔是一种反应性亲和标记物，可以通过点击反应附着到生物分子上。

酰肼

Hydrazides are carbonyl-reactive reagents for the labeling of aldehydes and ketones.
群组标签 Crosslinking, Biotinylation, Azides, Alkynes, Hydrazides, Click chemistry, Protein labeling
  • Azide-PEG4-hydrazide
    A bifunctional reagent containing the azide group and hydrazide function. It reacts with aldehydes and ketones. The azide group can then be coupled with various alkynes via CuAAC reaction.
  • Biotin-X-hydrazide
    Hydrazide biotin reagent with aminocaproic spacer useful for biotinylation of macromolecule reactive carbonyls.
  • 炔酰肼 (Alkyne hydrazide)
    含有炔基和酰肼官能团的双功能试剂。它与醛和酮发生反应。然后炔基可以通过 CuAAC 反应与各种叠氮化物偶联。

四嗪

Non-fluorescent tetrazines for inverse electron demand Diels-Alder reaction (IEDDA) with terminal alkenes and strained olefins, such as trans-cyclooctenes and some cyclooctynes.
群组标签 Crosslinking, Copper-free click chemistry, Tetrazines, Biotinylation, Azides, Click chemistry
  • Azide-PEG3-tetrazine
    A hydrophilic bifunctional linker with azide and tetrazine function groups flanking PEG3 (triethylene glycol) spacer.
  • Biotin-PEG4-tetrazine
    Biotin tetrazine is a reagent for copper-free click chemistry labeling with biotin, a well-known affinity probe to streptavidin.
  • PEG3-tetrazine
    PEG3 tetrazine is a mono-reactive triethyleneglycol with a tetrazine group for IEDDA conjugation with strained olefins.

羧酸

Carboxylic acids with reactive groups for the conjugation of different biomolecules.
群组标签 Crosslinking, PROTAC, Carboxylic acids, Azides, Alkynes, Halides, Click chemistry, Amines

卤化物

Halogen derivatives with reactive groups for bioconjugation.
群组标签 Crosslinking, Carboxylic acids, Azides, Alkynes, Halides, Click chemistry
  • Alkyne-PEG2-iodide
    Bifunctional reactive crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling, and reactive alkyl iodide group.
  • Alkyne-PEG3-iodide
    PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and click chemistry.
  • Alkyne-PEG4-iodide
    Bifunctional reactive PEG4-based crosslinker containing terminal alkyne group for click chemistry or Sonogashira coupling and reactive alkyl iodide group.
  • Azide-PEG2-iodide
    A bifunctional molecule containing hydrophilic PEG2 with azide and iodide groups.
  • Azide-PEG3-chloride
    Azide-PEG3-chloride contains a reactive halogen atom and an azide group for click chemistry reaction. It can also serve as a protected amine group equivalent.
  • Azide-PEG3-iodide
    Azide-PEG3-iodide is a bifunctional linker with a highly reactive alkylative halogen functional group and an azido group for click chemistry or Staudinger ligation.
  • Iodo-PEG3-carboxylic acid
    A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.
  • Iodo-PEG3-iodide
    Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.

点击化学配体和催化剂

Auxiliary reagents for click chemistry: catalysts, buffers, and ligands for copper-catalyzed click reaction (CuAAC).
群组标签 Click chemistry

生物结合辅助试剂

Auxiliary reagents, various buffers, and solvents for labeling and conjugation.
群组标签 Click chemistry

同型双功能试剂

Homobifunctional crosslinkers with identical reactive groups at opposite ends of the spacer for intramolecular crosslinks and chemical crosslinking of macromolecular chains.
群组标签 Crosslinking, NHS esters, Carboxylic acids, Azides, Halides, Click chemistry

马来酰亚胺

Maleimides are thiol-reactive compounds for labeling sulfhydryl (thiol) groups in proteins.
群组标签 Crosslinking, NHS esters, Copper-free click chemistry, Biotinylation, Cycloalkynes, Maleimides, Azides, Alkynes, Click chemistry

环炔烃

Highly reactive cycloalkynes for copper-free click reaction (SPAAC, strain-promoted azide-alkyne cycloaddition).
群组标签 Crosslinking, NHS esters, Copper-free click chemistry, STP esters, Cycloalkynes, Maleimides, Cyanine3, Click chemistry, Protein labeling, Amines
  • 3269-x，Cy3-PEG4-BCN（外切） [Cy3-PEG4-BCN (exo)]
    Cyanine3-PEG4-BCN 是一种用于叠氮基修饰的乙二醇分离式连接体，用于无铜点击偶联。
  • DBCO-NHS 酯
    偶氮二苯并环辛炔 (DBCO、ADIBO) 试剂用于应变促进的无铜点击化学 (SPAAC)。该试剂含有 NHS 酯官能团，用于将环辛炔连接到各种分子上。
  • DBCO-PEG6-NHS ester
    A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).
  • DBCO-STP酯 (DBCO-STP ester)
    一种活化酯用于蛋白质/抗体/肽的修饰，引入到无铜点击化学反应。
  • DBCO-amine trifluoroacetate
    Bifunctional linker containing dibenzocyclooctyne (DBCO, ADIBO) for strain-promoted copper-free click reaction (SPAAC) and free amine for the coupling with various electrophilic compounds like activated esters and epoxides.
  • DBCO-马来酰亚胺 (DBCO-maleimide)
    双功能连接体含有硫醇反应性马来酰亚胺基团和叠氮化物反应性二苯并环辛炔部分。
  • Exo-BCN-PNP
    BCN-PNP 碳酸酯是一种通过氨基甲酸酯与底物伯氨基连接引入 BCN 基团的工具。

硫醇类

Bifunctional reagents with a thiol (-SH) functional group. Thiols are nucleophilic compounds that participate in many reactions with electrophiles.
群组标签 Crosslinking, Thiols
  • Hydroxy-PEG2-thiol
    Short bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
  • Hydroxy-PEG3-thiol
    PEG3 bifunctional linker with thiol and hydroxyl groups. Thiol can coat gold surfaces forming a hydrophilic monolayer.
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