Oligonucleotide synthesis reagents

Oligonucleotide synthesis reagents / 产品分类和该类别中的产品
Reagents for oligonucleotide synthesis.

FAM amidites and supports

Fluorescein phosphoramidites and supports used for 3'-, internal, and 5'-modification of oligonucleotides.

Cyanine phosphoramidites

Cyanine dye phosphoramidites for the synthesis of 5'-modified oligos.

Quencher phosphoramidites and supports

Solid supports with fluorescence quenchers, and phosphoramidites for the labeling of terminal and internal positions of the oligonucleotide.
  • DusQ 1 CPG 1000
    Controlled pore glass (CPG) 1000 solid support for synthesis of oligonucleotides with 3’-terminal DusQ1 quencher. Compatible with standard deblocking conditions.
  • DusQ 1 CPG 500
    固体支持物-可控微孔玻璃 (CPG) 500,用于合成3' 末端带有 DusQ 1 猝灭剂的寡核苷酸。与标准解封闭条件兼容。
  • DusQ 1 amidite, 5'-terminal
    Terminal phosphoramidite for labeling oligonucleotides at the 5' end with DusQ 1 quencher.
  • DusQ 1 phosphoramidite
    A black quencher dye phosphoramidite for the synthesis of oligonucleotide probes labeled with DusQ 1 quenchers at 5’-terminal. Useful for HEX, JOE, ROX, Cyanine3.
  • DusQ 2 CPG 1000
    Controlled pore glass (CPG) 1000 modified support for the synthesis of oligonucleotides with DusQ 2 quencher at the 3’ end. Compatible with standard deblocking conditions.
  • DusQ 2 CPG 500
    Controlled pore glass (CPG) 500 modified support for the synthesis of oligonucleotides with DusQ 2 quencher at the 3’ end. Compatible with standard deblocking conditions.
  • DusQ 2 dT 亚磷酰胺 (DusQ 2 dT phosphoramidite)
    用于寡核苷酸 DusQ 2 dT 标记的亚磷酰胺。
  • DusQ 2 phosphoramidite
    DusQ 2 phosphoramidite for the synthesis of oligonucleotides labeled with DusQ 2 quencher at 3'-end, 5'-end and internal position. The phosphoramidite has DMT protection and can be used for cartridge purification.
  • DusQ 21 CPG 500
    DusQ 21 is a quencher for dyes in red part of the spectrum, including Cyanine5 and Cyanine5.5.
  • DusQ 3 CPG 500
    DusQ 3 is a dark quencher for far red and near infrared dyes like Cyanine5.5. This is a controlled pore glass solid support for the synthesis of oligonucleotides with the quencher attached to 3'-terminus.
  • DusQ1 dT 亚磷酰胺 (DusQ 1 dT phosphoramidite)
    用于寡核苷酸DusQ1 dT 标记的亚磷酰胺。

Universal solid supports

Non-nucleosidic controlled pore glass (CPG) support with universal linkers for the solid phase oligonucleotide automated synthesis of the sequence with any nucleoside at 3'-terminus.
  • MGB CPG 1000
    MGB CPG 1000 用于合成含有二氢吡咯并吲哚三肽的寡核苷酸,用于与DNA 小沟结合。
  • Universal CPG type II, 500A
    This universal support is intended for automated synthesis of oligonucleotides for short-term dephosphorylation process during deblocking. Pore size of 500 Å is recommended for the synthesis of oligonucleotides up to 50 bases.
  • 通用 CPG II 型,1000A (Universal CPG type II, 1000A)
    这种通用支持物旨在用于寡核苷酸的自动合成,以加速解封闭过程中的去磷酸化过程。对于多达 120 个碱基的寡核苷酸合成,建议使用 1000 Å 的孔径。

Click chemistry amidites and supports

Phosphoramidites and solid supports for the synthesis of oligonucleotides with azide and alkyne groups capable of downstream Click chemistry modification.

Phosphorylation amidites and supports

Reagents and solid supports for the solid phase synthesis of 3'- and 5’-phosphorylated oligonucleotides.

Amino amidites and supports

Reagents for the synthesis of amino modified oligonucleotides, which can be further modified or immobilized on certain solid supports.

Biotinylation amidites and supports

Phosphoramidites and solid supports for the incorporation of biotin moiety into oligonucleotides.

Spacer phosphoramidites

Spacer modifiers to insert linkers and spacer arms into oligonucleotides, and to prepare branched oligonucleotides.

Polyaromatic phosphoramidites

Phosphoramidites with polycyclic aromatic hydrocarbons (PAHs) moieties for the introduction of polyaromatic residues in solid-phase synthesised oligonucleotides.

Modified nucleobase amidites

Non-standard nucleobase phosphoramidites suitable for solid phase synthesis of modified oligonucleotides.

Sulfurization reagents

Reagents for the synthesis of phosphothioate oligomers via amidite chemistry.
  • DDTT Sulfurizing Reagent
    DDTT Sulfurizing Reagent for the fast and efficient production of phosphorothioate oligonucleotides (PTOs).
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