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(E/Z)-4-Hydroxytamoxifen

目录号 数量 价格 提前通知时间
3669-10mg 10 mg $60 现货
3669-50mg 50 mg $209 现货
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(E/Z)-4-Hydroxytamoxifen (4-OHT, cis/trans-4-hydroxytamoxifen, afimoxifene) is a selective estrogen receptor (ER) modulator, an active metabolite of tamoxifen. 4-Hydroxytamoxifen is widely used as a research tool for inducible genome manipulation.

4-Hydroxytamoxifen is used in the inducible Cre-LoxP system to control CreER/CreERT2 recombinase activity and trigger tissue-specific gene expression or genome/genetic modification (e.g., gene deletion). 4-Hydroxytamoxifen is a part of the TRAP/TRAP2 (targeted recombination in active populations) systems providing genetic access to neuron activity. It is also used in CRISPR/Cas9 gene editing to activate inactivated Cas9 nuclease.

Also, 4-Hydroxytamoxifen was reported to be an intramembranous lipid peroxidation inhibitor, exhibiting peroxyl radical scavenging activity.

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AF 647 NHS 酯 (AF 647 NHS ester)

明亮的水溶性琥珀酰亚胺酯AF 647染料,用于蛋白质和抗体标记。
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AF 488 amine

AF 488 dye with a terminal amino group with emission in the green region of the spectrum.

氨基-11-ddUTP (Amino-11-ddUTP)

Amino-11-ddUTP 是一种用于修饰 DNA 的三磷酸盐。
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General properties

Appearance: white solid
Molecular weight: 387.52
CAS number: 68392-35-8
Molecular formula: C26H29NO2
IUPAC name: 4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol
Solubility: DMF, Ethanol, DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表(MSDS): 下载
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