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Alkyne dT phosphoramidite

目录号 数量 价格 提前通知时间
1897-100mg 100 mg $330 $195 现货
1897-1g 1 g $2590 $1250 现货
1897-5g 5 g $9900 $2850 现货
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This reagent is designed for the synthesis of oligonucleotides bearing triple bond (alkyne) in the middle of the chain. Alkyne is attached to the deoxyuridine fragment, and it does not interfere with the hybridization of the complementary strand. This allows the preparation of modified oligonucleotide probes bearing fluorescent dyes, quenchers, and other fragments attached to the middle of the chain by virtue of copper-catalyzed Click chemistry reaction with various azides.

This phosphoramidite is solid, so it is easy to dispense and handle. It is compatible with the standard deblocking conditions.

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TBTA ligand

TBTA is one of the most widely used water-insoluble ligands for copper-catalyzed azide-alkyne cycloadditions (CuAAC).

FAM 亚磷酰胺,6-异构体 (FAM phosphoramidite, 6-isomer)

单一构体 6-FAM 亚磷酰胺,用于寡核苷酸的修饰。

六乙二醇亚磷酰胺 (Hexaethylene glycol phosphoramidite)

间隔基亚磷酰胺 18(六乙二醇亚酰胺)为寡核苷酸合成提供一个长的亲水性连接基。

General properties

Appearance: off white solid
Mass spec M+ increment: 437.1
Molecular weight: 877.96
Molecular formula: C48H56N5O9P
Solubility: good in acetonitrile, DCM
Quality control: NMR 1H, NMR 31P, HPLC-MS
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表(MSDS): 下载
产品规格

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases
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