Alkyne-PEG4-phosphoramidite
| 目录号 | 数量 | 价格 | 提前通知时间 | 购买此产品 |
|---|---|---|---|---|
| 2779-100mg | 100 mg | $390 | 现货 | |
| 2779-250mg | 250 mg |
$680
|
现货 | |
| 2779-1g | 1 g |
$1640
|
现货 | |
| 2779-5g | 5 g | 请查询 | 现货 |
Alkyne-PEG4-phosphoramidite is a tetraethylene glycol phosphoramidite with a terminal triple bond that can be used for the synthesis of various functionalized oligonucleotides. An alkyne fragment in the resulting molecules reacts in Click Chemistry reactions with azide-containing compounds in the presence of copper (I) salts to produce various oligonucleotide conjugates, such as those with dyes, peptides, or glycans. The yield of resulting compounds is rather high, their isolation and purification are often easier than those of molecules produced by the interaction of amino-modified oligonucleotides with activated esters such as those of dyes. Click Chemistry reactions are bioorthogonal because neither terminal alkyne nor azide functional groups usually are found in biomolecules.
A tetraethylene glycol linker in phosphoramidite gives it higher hydrophilic properties and reduces toxicity and immunogenicity of produced conjugates.
Recommendations for using the reagent:
Solvent: Acetonitrile.
Recommended condensation time: Standard, as for natural nucleoside phosphoramidites.
It is recommended to use standard deprotection conditions.
顾客还购买了这个产品
LumiMount® Fluorescence Mounting Medium
An aqueous anti-fade mounting medium for coverslipping cells and tissues stained with various fluorescent dyes.AF 488 DBCO
含有绿色荧光团 AF 488的二苯并环辛炔（DBCO、ADIBO），可用于标记活细胞、整个生物体和无生命样品内的叠氮化物生物分子。纯5-异构体。sulfo-Cyanine5 dUTP
sulfo-Cyanine5 dUTP is a fluorescently labeled triphosphate used to enzymatically modify DNA with a sulfo-Cyanine5 fluorophore. The reagent contains a long linker arm, which makes incorporation highly efficient.
将此产品添加到购物车中并获得免费的快递服务
General properties
| Appearance: | colorless or yellow oil |
| Molecular weight: | 432.49 |
| CAS number: | 1682657-14-2 |
| Molecular formula: | C20H37N2O6P |
| IUPAC name: | 2-cyanoethyl (3,6,9,12-tetraoxapentadec-14-yn-1-yl) diisopropylphosphoramidite |
| Solubility: | good in acetonitrile and dichloromethane |
| Quality control: | NMR 1H and 31P, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| 安全数据表（MSDS）: | 下载 |
| 产品规格 |
Oligo synthesis details
| Diluent: | acetonitrile |
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Deprotection conditions: | identical to protected nucleobases |
您的购物车是空的
$ 
