Alkyne-PEG4-maleimide
目录号 | 数量 | 价格 | 提前通知时间 | 购买此产品 |
---|---|---|---|---|
2002-100mg | 100 mg | $150 | 现货 | |
2002-1g | 1 g | $590 | 现货 |
When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has length of 14Å (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules.
Maleimide functional group is especially useful, because they can label proteins site specifically. Most proteins have only limited number of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAC (copper-catalyzed alkyne-azide cycloaddition).
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抗坏血酸 (Ascorbic acid)
抗坏血酸是一种还原剂,可将铜 (II) 转化为用于催化点击反应的一价形式。Azide-PEG4-amine
PEG4 amine azide is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.Copper(II)-THPTA catalytic buffer, 1.5x
Ready-to-use catalytic buffer containing сopper(II) and water-soluble THPTA ligand. It is suitable for click chemistry modification of proteins.General properties
Appearance: | yellow oil |
Mass spec M+ increment: | 311.3 |
Molecular weight: | 311.33 |
CAS number: | 1262681-30-0 |
Molecular formula: | C15H21NO6 |
Solubility: | good in water, DMF, DMSO |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
安全数据表(MSDS): | 下载 |
产品规格 |