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Alkyne-PEG4-maleimide

目录号 数量 价格 提前通知时间
2002-100mg 100 mg $150 现货
2002-1g 1 g $590 现货
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When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has length of 14Å (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules.

Maleimide functional group is especially useful, because they can label proteins site specifically. Most proteins have only limited number of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAC (copper-catalyzed alkyne-azide cycloaddition).

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Azide-PEG6-NHS ester

A hydrophilic bifunctional linker with azide and NHS ester function groups flanking PEG6 (hexaethylene glycol).

AF 488 alkyne

Alkyne derivative of AF 488 dye for copper-catalyzed cycloaddition to azides. Pure 5-isomer.

炔酰肼 (Alkyne hydrazide)

含有炔基和酰肼官能团的双功能试剂。它与醛和酮发生反应。然后炔基可以通过 CuAAC 反应与各种叠氮化物偶联。

General properties

Appearance: yellow oil
Mass spec M+ increment: 311.3
Molecular weight: 311.33
CAS number: 1262681-30-0
Molecular formula: C15H21NO6
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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