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AmdU (5-Azidomethyl-2'-deoxyuridine)

目录号 数量 价格 提前通知时间
B1540 5 mg $120 现货
D1540 25 mg $255 现货
F1540 100 mg $890 现货
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Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similar to EdU.

In contrast to EdU which needs to be further modified with azides in the presence of the copper catalyst, AmdU can also react in the absence of copper catalyst using SPAAC click chemistry with strained cycloalkynes, such as cyclooctynes. This enables the detection of nascent DNA in benign, copper-free conditions.

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DBCO-PEG6-NHS ester

A heterobifunctional linker with DBCO and NHS ester function groups flanking PEG6 (hexaethylene glycol).

Biotin-PEG3-azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe to streptavidin.

AF 343 (Coumarin)-X-azide

AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.

General properties

Appearance: white / off white solid
Molecular weight: 283.24
CAS number: 59090-48-1
Molecular formula: C10H13N5O5
IUPAC name: 5-Azidomethyl-2'-deoxyuridine
Solubility: in water, alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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