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DusQ® 1 CPG 1000

CPG改性固体载体 DusQ® 1

目录号	数量	价格	提前通知时间
14960	100 mg	$144	现货
34960	500 mg	$530	现货
44960	1 g	$960	现货
54960	5 g	请查询	现货

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This support with a pore size of 1000 Å is intended for the automated synthesis of oligonucleotides of up to 120 bases in length modified with DusQ 1 dark quencher at the 3’ end.

Non-fluorescent DusQ 1 quencher exhibits the strongest absorption within the range of 480 to 580 nm; its absorption maximum is at 534 nm. It is suitable for quenching (a combination of static and dynamic quenching) of many fluorophores, including Biosearch Blue™, Marina Blue™, Edans, Bothell Blue, FAM™, JOE™, VIC™, R6G, HEX™, TET™ and Yakima Yellow™. It can be used for the synthesis of hybridization probes such as TaqMan, Molecular Beacon, Scorpion.

Usage

Coupling: Standard conditions identical to normal nucleobases.

Deprotection: 2 hours at room temperature using concentrated ammonia or 10 min at 65 °C using AMA mixture, concentrated aqueous ammonia/40% methylamine (1:1). Deprotection conditions depend on oligonucleotide composition and nucleobase protecting groups, as well as additional modifications, if present.

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Alkyne dT phosphoramidite

Phosphoramidite modifier for synthesizing oligonucleotides containing alkyne modification in the middle of the chain.

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通用 CPG II 型，1000A (Universal CPG type II, 1000A)

这种通用支持物旨在用于寡核苷酸的自动合成，以加速解封闭过程中的去磷酸化过程。对于多达 120 个碱基的寡核苷酸合成，建议使用 1000 Å 的孔径。

SIMA azide, 6-isomer

Azide of green-yellow emitting dye SIMA for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.

General properties

Appearance:	red beads
Quality control:	NMR ¹H and HPLC-MS (95%) of bound reagent, loading measurement, functional testing in oligo synthesis.
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
安全数据表（MSDS）:	下载
	产品规格

Spectral properties

Excitation/absorption maximum, nm:	522
ε, L⋅mol⁻¹⋅cm⁻¹:	27300
CF₂₆₀:	0.17
CF₂₈₀:	0.10

Oligo synthesis details

Pore size, Å:	1000
Typical loading, umol/g:	30−50

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.