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Biotin-11-dUTP

目录号 数量 价格 提前通知时间
1553-250nmol 250 nmol $140 20 天
1553-500nmol 500 nmol $235 现货
1553-1umol 1 umol $360 现货
1553-5umol 5 umol 请查询 现货
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Biotinylated deoxyuridine triphosphate (dUTP) can be used for DNA labeling using various methods, including Nick-translation and 3’-terminal non-radioactive labeling. Generated probes can be used in various hybridization experiments such as Southern blot, Northern blot, dot blot, or FISH. Biotin-labeled probes are detected with horseradish peroxidase-conjugated streptavidin or other biomolecule conjugates binding biotin.

«11» in the compound name indicates the length of the linker between dUTP and biotin; this linker increases the efficiency of labeled dUTP incorporation into DNA and interaction of biotin with specific proteins such as avidin/streptavidin or anti-biotin antibodies.

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F-ara-EdU(2'-脱氧-2'-氟-5-乙炔尿苷) [F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)]

F-ara-EdU (2'-脱氧-2'-氟-5-乙炔尿苷) 是胸苷的合成类似物,用于研究 DNA 从头合成和细胞增殖。它是一种替代 BrdU(5-溴 -2'-脱氧尿苷)和 EdU(5-乙炔基-2'-脱氧尿苷)并且细胞毒性较小的药品。

General properties

Appearance: colorless solid
Molecular weight: 878.54
Molecular formula: C28H40N6Li3O17P3S
IUPAC name: ((2R,3S,5R)-5-(2,4-dioxo-5-(3-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)prop-1-yn-1-yl)-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate
Solubility: soluble in water
Quality control: HPLC-MS (95%), testing in enzymatic reaction
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid excessive freeze-thaw cycles.
安全数据表(MSDS): 下载
产品规格

产品引用

  1. Krasikova, A.; Kulikova, T.; Schelkunov, M.; Makarova, N.; Fedotova, A.; Plotnikov, V.; Berngardt, V.; Maslova, A.; Fedorov, A. The First Chicken Oocyte Nucleus Whole Transcriptomic Profile Defines the Spectrum of Maternal MRNA and Non-Coding RNA Genes Transcribed by the Lampbrush Chromosomes. Nucleic Acids Research, 2024, 52(21), 12850–12877. doi: 10.1093/nar/gkae941
  2. Krasikova, A.; Kulikova, T.; Rodriguez Ramos, J. S.; Maslova, A. Assignment of the Somatic A/B Compartments to Chromatin Domains in Giant Transcriptionally Active Lampbrush Chromosomes. Epigenetics & Chromatin, 2023, 16(1), 24. doi: 10.1186/s13072-023-00499-2
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