Biotin-PEG3-azide
目录号 | 数量 | 价格 | 提前通知时间 | 购买此产品 |
---|---|---|---|---|
C3730 | 10 mg | $125 | 现货 | |
D3730 | 25 mg | $220 | 现货 | |
E3730 | 50 mg | $325 | 现货 | |
F3730 | 100 mg | $450 | 现货 | |
K3730 | 1 g | $1420 | 现货 |
Biotin-PEG3-azide is a click chemistry biotinylation tool. This reagent allows the labeling of alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin via copper-catalyzed or copper-free click reaction. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection.
This structure of biotin azide features a long hydrophilic PEG3 linker that separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker also enhances aqueous solubility to facilitate conjugation.
The azide can be conjugated with various molecules using our recommended protocol.
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AF 343 (Coumarin)-X-azide
AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.AF 488 streptavidin
AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.General properties
Appearance: | colorless solid |
Molecular weight: | 400.50 |
CAS number: | 1910803-72-3 |
Molecular formula: | C16H28N6O4S |
Solubility: | soluble in DMF, DMSO, moderately soluble in water |
Quality control: | NMR 1H (95%) and 13C, TLC, functional testing |
Storage conditions: | Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. |
安全数据表(MSDS): | 下载 |
产品规格 |
产品引用
- Liang, J.; Han, J.; Gao, X.; Jia, H.; Li, R.; Tse, E. C. M.; Li, Y. Clickable APEX2 Probes for Enhanced RNA Proximity Labeling in Live Cells. Anal. Chem., 2024, 96(2), 685–693. doi: 10.1021/acs.analchem.3c03614
- Edr, A.; Wrobel, D.; Krupková, A.; Šťastná, L. Č.; Cuřínová, P.; Novák, A.; Malý, J.; Kalasová, J.; Malý, J.; Malý, M.; Strašák, T. Adaptive Synthesis of Functional Amphiphilic Dendrons as a Novel Approach to Artificial Supramolecular Objects. International Journal of Molecular Sciences, 2022, 23(4), 2114. doi: 10.3390/ijms23042114
- Shen, J.Z.; Qiu, Z.; Wu, Q.; Finlay, D.; Garcia, G.; Sun, D.; Rantala, J.; Barshop, W.; Hope, J.L.; Gimple, R.C.; Sangfelt, O.; Bradley, L.M.; Wohlschlegel, J.; Rich, J.N.; Spruck, C. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell, 2021, 184(2), 352–369.e23. doi: 10.1016/j.cell.2020.11.042
- Zeng, Q.; Deng, H.; Li, Y.; Fan, T.; Liu, Y.; Tang, S.; Wei, W.; Liu, X.; Guo, X.; Jiang, J.; Wang, Y.; Song, D. Berberine Directly Targets the NEK7 Protein to Block the NEK7–NLRP3 Interaction and Exert Anti-inflammatory Activity. Journal of Medicinal Chemistry, 2021, 64(1), 768–781. doi: 10.1021/acs.jmedchem.0c01743