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Coumarin 343 azide

此产品已停产，不再提供.
 我们建议使用AF 343 (Coumarin) X azide作为替代品
Azides AF 343 (Coumarin) Click chemistry

This product will be discontinued soon in favor of Coumarin 343 X azide. We may still have some material in stock (please see availability above).

This greenish-blue emitting fluorophore can be used as a FRET donor for FAM. Azide derivative is suitable for click chemistry.

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AF 343 (Coumarin) X azide

AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.

AMCA carboxylic acid

Non-reactive form of AMCA fluorescent dye with a free carboxyl group. AMCA is one of the brightest blue fluorescent dyes with large Stoke's shift and high resistance to photobleaching.

Cyanine5炔烃 (Cyanine5 alkyne)

Cyanine5 alkyne 是一种用于生物分子点击化学标记的炔烃染料。

General properties

Appearance: yellow powder
Molecular weight: 441.48
CAS number: 1807503-82-7
Molecular formula: C22H27N5O5
Solubility: Good in organic solvents (DCM, chloroform, DMF, DMSO, MeCN, alcohols), poor in water
Quality control: NMR 1H (95%) TLC, functional testing
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
安全数据表（MSDS）: 下载
产品规格

Spectral properties

Excitation/absorption maximum, nm: 437
ε, L⋅mol−1⋅cm−1: 39000
Emission maximum, nm: 477
Fluorescence quantum yield: 0.63
CF260: 0.29
CF280: 0.24

产品引用

  1. Musiol-Kroll, E.M.; Zubeil, F.; Schafhauser, T.; Härtner, T.; Kulik, A.; McArthur, J.B.; Koryakina, I.; Wohlleben, W.; Grond, S.; Williams, G.J.; Lee, S.Y.; Weber, T. Polyketide bio-derivatization using the promiscuous acyltransferase KirCII. ACS Synthetic Biology, 2017, 6(3), 421–427. doi: 10.1021/acssynbio.6b00341
  2. Teske, N.S.; Voigt, J.; Shastri, V.P. Clickable Degradable Aliphatic Polyesters via Copolymerization with Alkyne Epoxy Esters: Synthesis and Postfunctionalization with Organic Dyes. Journal of the American Chemical Society, 2014, 136(29), 10527-10533. doi: 10.1021/ja505629w
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