菁染料5 DBCO (Cyanine5 DBCO)

环炔烃无铜点击化学花青5

目录号	数量	价格	提前通知时间
A30F0	1 mg	$125	10 天
B30F0	5 mg	$260	10 天
C30F0	10 mg	$325	21 天
D30F0	25 mg	$510	10 天
E30F0	50 mg	$895	10 天
F30F0	100 mg	$1490	10 天

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是Cyanine5的衍生物，发红色荧光，具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团，用于无铜条件的链接化学。在没有铜催化剂的情况下，应变环炔烃基，例如环辛炔，能快速地与叠氮化物发生应变促进的炔叠氮化物环加成（spAAC）反应。该反应非常快速、温和且具有生物相容性。与其他环炔烃相比，DBCO 提供最快的反应动力学，同时仍具有良好的稳定性。

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FAM 胺，5-异构体 (FAM amine, 5-isomer)

荧光素的氨基衍生物，纯5-异构体。在脂肪胺基团和荧光团之间包含一个连接臂。可用于酶促转氨基反应的标记、与亲电试剂的反应以及胺化还原反应。

BDP® 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.

sulfo-Cyanine5.5 DBCO

Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free click reaction with azides.

外观:
质谱 M+ 增量:	928.4
分子量:	929.03
分子式:	C₅₃H₅₉N₄F₆O₂P
溶解度:
质量控制:
储存条件:
安全数据表（MSDS）:	下载
	产品规格

激发/吸收极大值，纳米:	646
ε, 摩尔吸光系数，cm⁻¹:	250000
发射极大值，纳米:	662
荧光量子产率:	0.2

产品引用

Toro-González, M.; Akingbesote, N.; Bible, A.; Pal, D.; Sanders, B.; Ivanov, A. S.; Jansone-Popova, S.; Popovs, I.; Benny, P.; Perry, R.; Davern, S. Development of ²⁵⁵Ac-Doped Biocompatible Nanoparticles for Targeted Alpha Therapy. Journal of Nanobiotechnology, 2024, 22(1), 306. doi: 10.1186/s12951-024-02520-6
Wang, Y.-J.; Li, L.; Yu, J.; Hu, H.-Y.; Liu, Z.-X.; Jiang, W.-J.; Xu, W.; Guo, X.-P.; Wang, F.-S.; Sheng, J.-Z. Imaging of Escherichia Coli K5 and Glycosaminoglycan Precursors via Targeted Metabolic Labeling of Capsular Polysaccharides in Bacteria. Sci. Adv., 2023, 9(7), eade4770. doi: 10.1126/sciadv.ade4770
Borner, T.; Tinsley, I. C.; Milliken, B. T.; Doebley, S. A.; Najjar, N. R.; Kerwood, D. J.; De Jonghe, B. C.; Hayes, M. R.; Doyle, R. P. Creation of a Peptide Antagonist of the GFRAL–RET Receptor Complex for the Treatment of GDF15-Induced Malaise. J. Med. Chem., 2023, 66(16), 11237–11249. doi: 10.1021/acs.jmedchem.3c00667
Miranda, A.; Lopez-Blanco, R.; Lopes-Nunes, J.; Melo, A.M.; Campello, M.P.C.; Paulo, A.; Oliveira, M.C.; Mergny, J.-L.; Oliveira, P.A.; Fernandez-Megia, E.; Cruz, C. Gallic Acid–Triethylene Glycol Aptadendrimers Synthesis, Biophysical Characterization and Cellular Evaluation. Pharmaceutics, 2022, 14(11), 2456. doi: 10.3390/pharmaceutics14112456