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L-Alanine-d3

目录号 数量 价格 提前通知时间
4978-100mg 100.0 mg
$112.00
7 天
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L-Alanine-d3 is the deuterium-labeled L-alanine and is intended for use as an analytical reference standard in LC-MS/MS.

Alanine is one of the principal amino acid substrates for hepatic gluconeogenesis and ureagenesis. Alanine is produced in peripheral tissues in transamination processes with glutamate, branched-chain amino acids, and other amino acids; following its release in the systemic circulation, alanine is predominantly taken up by the liver and to a lesser extent by the kidney. High alanine levels (hyperalaninemia) could be a marker for liver disease, diabetes mellitus, muscle breakdown, or genetic disorders like pyruvate dehydrogenase deficiency and alanine-glyoxylate aminotransferase 2 (AGXT2) deficiency. Low level of alanine (hypoalaninemia) could be marker of hypoglycemia or ketoacidosis.

Quantification of this important metabolite and biomarker in dried blood samples can be performed most efficiently by LC-MS/MS using Alanine-d3 as a standard.

General properties

Appearance: white solid
Molecular weight: 92.11
Molecular formula: C3H4D3NO2
Solubility: in water
Quality control: NMR 1H and HPLC-MS (95+ %, D: 98+ %)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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