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Orotic acid (1,3-15N2) monohydrate

目录号 数量 价格 提前通知时间
5354-1mg 1.0 mg
$126
 12 天
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Orotic acid-1,3-15N2 (monohydrate) is the orotic acid labeled with a stable isotope of nitrogen and is intended for use as an internal standard for the quantification of orotic acid by GC- or LC-MS.

Orotic acid (6-Carboxyuracil) is an intermediate compound in the biosynthetic pathway of pyrimidines (orotic acid is converted to UMP by UMP synthase), primarily sourced in the body through a series of enzymatic reactions involving carbamoyl phosphate synthase II. Its production is influenced by various factors such as positive feedback from 5-phosphoribosyl-1-pyrophosphate and negative feedback from uridine triphosphate. The measurement of urinary orotic acid is useful in confirming the diagnosis of hereditary metabolic diseases. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders.

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General properties

Appearance: beige solid
Molecular weight: 176.10
CAS number: 147687-63-6
Molecular formula: C5H4(15N)2O4•H2O
IUPAC name: 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid-15N2 Monohydrate
Solubility: DMSO
Quality control: NMR 1H and HPLC-MS (95+ %, N: 98+ %)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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产品规格
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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