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SiRhius® 650 azide

目录号 数量 价格 提前通知时间
11S30 1 mg
$199.00
现货
21S30 5 mg
$499.00
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51S30 50 mg
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SiRhius® 650 azide is a far-red fluorescent dye functionalized with an azide group for bioorthogonal labeling via click chemistry. The probe is designed for rapid and selective conjugation to alkyne-bearing biomolecules using copper-catalyzed (CuAAC) or strain-promoted (SPAAC) cycloaddition reactions.

The SiRhius® 650 fluorophore exhibits excitation and emission maxima in the far-red region (~650/670 nm), enabling deep tissue penetration and low background autofluorescence. Its high molar absorptivity and quantum yield provide a bright signal, while the photostable scaffold enables extended imaging applications, including live-cell and super-resolution microscopy.

The azide functionality is chemically stable under physiological conditions yet highly reactive in click reactions, allowing efficient labeling of proteins, nucleic acids, lipids, and other biomolecules modified with terminal alkynes. The relatively compact size of the azide group minimizes perturbation of the target molecule, preserving biological function.

SiRhius 650® azide is suitable for fluorescence microscopy, flow cytometry, and in vitro or in vivo imaging workflows where far-red emission and high specificity of labeling are required.

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General properties

Appearance: light-blue crystals
Molecular weight: 554.71
CAS number: 3031722-00-3
Molecular formula: C30H34N6O3Si
Solubility: DCM, acetonitrile, triethylamine, DMF, DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表(MSDS): 下载
产品规格

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 112000
Emission maximum, nm: 669
Fluorescence quantum yield: 0.57
CF260: 0.07
CF280: 0.02
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