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Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)

目录号 数量 价格 提前通知时间
3431-5mg 5 mg $129 现货
3431-25mg 25 mg $240 现货
3431-100mg 100 mg $630 现货
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The tetraacetylated N-(4-pentynoyl)-mannosamine (Ac4ManNAl) is an alkyne-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4ManNAl is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-acetylmannosamine (ManNAc).

The resulting alkyne-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) click reaction with either fluorescent-labeled azides or biotin-azide.

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HPG (L-Homopropargylglycine)

Noncanonical amino acid analog of methionine with a terminal alkyne moiety for nascent protein synthesis detection.

THPTA配体

THPTA 是 Cu(I) 催化点击化学的水溶性配体。该配体使铜稳定在 Cu(I) 氧化态。由于水溶性高,与该配体的反应不需要有机共溶剂。

AF 488 叠氮化物 (AF 488 azide)

AF 488 叠氮化物是一种发射在绿色光谱范围内的荧光团。它与炔烃在铜催化的条件下发生环加成反应。

General properties

Appearance: white powder
Molecular weight: 427.41
CAS number: 935658-93-8
Molecular formula: C19H25NO10
IUPAC name: 2-deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-1,3,4,6-Tetraacetate-D-Mannopyranose
Solubility: DMSO, DMF, DCM, THF, Chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表(MSDS): 下载
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