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Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)

Azides Copper-free click chemistry Click chemistry
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3706-5mg 5 mg $129 现货
3706-25mg 25 mg $240 现货
3706-100mg 100 mg $630 现货
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The tetraacetylated N-Azidoacetyl-galactosamine (Ac4GalNAz) is an azide-labeled monosaccharide that provides a highly specific tool for studying glycoproteins through metabolic labeling in vivo and subsequent chemoselective ligation.

Ac4GalNAz is cell-permeable unnatural sugar that is intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylgalactosamine (GalNAc).

The resulting azide-contained glycoprotein can be detected via Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) click reaction with either fluorescent-labeled alkynes/cycloalkynes or biotin-alkyne.

The recommended concentration for cell labeling is 25-75 μM, and this concentration range may be a starting point for an individual experiment setup.

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FAM DBCO, 6-isomer

Cyclooctyne derivative of fluorescein (FAM) for copper-free click chemistry reaction with azides. Pure 6-isomer of fluorescein.

AmdU (5-Azidomethyl-2'-deoxyuridine)

Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.

General properties

Appearance: white crystals
Molecular weight: 430.37
CAS number: 653600-56-7
Molecular formula: C16H22N4O10
Solubility: DMSO, DMF, DCM, THF, Chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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产品规格
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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