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Alkyne dT phosphoramidite

炔烃寡核苷酸合成点击化学亚磷酰胺

目录号	数量	价格	提前通知时间
1897-100mg	100 mg	$330 $195	现货
1897-1g	1 g	$2590 $1250	现货
1897-5g	5 g	$9900 $2850	现货

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This reagent is designed for the synthesis of oligonucleotides bearing triple bond (alkyne) in the middle of the chain. Alkyne is attached to the deoxyuridine fragment, and it does not interfere with the hybridization of the complementary strand. This allows the preparation of modified oligonucleotide probes bearing fluorescent dyes, quenchers, and other fragments attached to the middle of the chain by virtue of copper-catalyzed Click chemistry reaction with various azides.

This phosphoramidite is solid, so it is easy to dispense and handle. It is compatible with the standard deblocking conditions.

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生物素亚磷酰胺（羟基脯氨醇） [Biotin phosphoramidite (hydroxyprolinol)]

生物素亚磷酰胺用于合成生物素化的寡核苷酸。含有二甲氧基三苯甲基基团。

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TBTA ligand

TBTA is one of the most widely used water-insoluble ligands for copper-catalyzed azide-alkyne cycloadditions (CuAAC).

Azide-PEG6-NHS ester

A hydrophilic bifunctional linker with azide and NHS ester function groups flanking PEG6 (hexaethylene glycol).

General properties

Appearance:	off white solid
Mass spec M+ increment:	437.1
Molecular weight:	877.96
Molecular formula:	C₄₈H₅₆N₅O₉P
Solubility:	good in acetonitrile, DCM
Quality control:	NMR ¹H, NMR ³¹P, HPLC-MS
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表（MSDS）:	下载
	产品规格

Oligo synthesis details

Diluent:	acetonitrile
Coupling conditions:	standard coupling, identical to normal nucleobases
Cleavage conditions:	ammonia, 2 h at room temperature
Deprotection conditions:	identical to protected nucleobases

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.