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Alkyne dT phosphoramidite

目录号 数量 价格 提前通知时间
1897-100mg 100 mg $330 $195 现货
1897-1g 1 g $2590 $1250 现货
1897-5g 5 g $9900 $2850 现货
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This reagent is designed for the synthesis of oligonucleotides bearing triple bond (alkyne) in the middle of the chain. Alkyne is attached to the deoxyuridine fragment, and it does not interfere with the hybridization of the complementary strand. This allows the preparation of modified oligonucleotide probes bearing fluorescent dyes, quenchers, and other fragments attached to the middle of the chain by virtue of copper-catalyzed Click chemistry reaction with various azides.

This phosphoramidite is solid, so it is easy to dispense and handle. It is compatible with the standard deblocking conditions.

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DusQ 2 CPG 500

Controlled pore glass (CPG) 500 modified support for the synthesis of oligonucleotides with DusQ 2 quencher at the 3’ end. Compatible with standard deblocking conditions.
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磷酸盐 CPG 500 固体支持物 (Phosphate CPG 500 solid support)

用于合成 3'-磷酸化寡核苷酸的 CPG 固体支持物。

Azide-PEG3-azide

Triethylene glycol diazide is a bifunctional crosslinker bearing two azide groups. Suitable for click chemistry.

General properties

Appearance: off white solid
Mass spec M+ increment: 437.1
Molecular weight: 877.96
Molecular formula: C48H56N5O9P
Solubility: good in acetonitrile, DCM
Quality control: NMR 1H, NMR 31P, HPLC-MS
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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产品规格

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases
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