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Hexynoic acid NHS ester
| 目录号 | 数量 | 价格 | 提前通知时间 | 购买此产品 |
|---|---|---|---|---|
| 41720 | 25 mg | $95 | 现货 | |
| 51720 | 50 mg | $180 | 现货 | |
| 61720 | 100 mg | $290 | 现货 | |
| 91720 | 1 g | 请查询 | 现货 |
Hexynoic acid NHS ester is an alkyne-containing NHS ester for the modification of biomolecules. Alkyne groups for copper-catalyzed click chemistry reaction are nearly never encountered in natural molecules. However, this NHS ester allows to attach alkyne groups to amino groups, which are ubiquitous in nature, and which are present in proteins, peptides, synthetic amino-DNA and numerous small molecules. Alkyne groups can be subsequently modified and conjugated by copper-catalyzed click reaction.
This reagent is a derivative of hexynoic acid.
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胺反应性、活化的 TAMRA 染料 N-羟基琥珀酰亚胺酯，用于标记蛋白质、多肽和氨基寡核苷酸的胺基。纯5-异构体。Cyanine5炔烃 (Cyanine5 alkyne)
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| Appearance: | yellowish oil / off white crystals |
| Mass spec M+ increment: | 94.0 |
| Molecular weight: | 209.20 |
| CAS number: | 906564-59-8 |
| Molecular formula: | C10H11NO4 |
| IUPAC name: | 5-Hexynoic acid, 2,5-dioxo-1-pyrrolidinyl ester |
| Solubility: | good in organic solvents (DMF, DMSO, DCM) |
| Quality control: | NMR 1H 95+% |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| 安全数据表（MSDS）: | 下载 |
| 产品规格 |
产品引用
- Monakhova, M. V.; Kubareva, E. A.; Kolesnikov, K. K.; Anashkin, V. A.; Kosaretskiy, E. M.; Zvereva, M. I.; Romanova, E. A.; Friedhoff, P.; Oretskaya, T. S.; Zatsepin, T. S. Reactive Acrylamide-Modified DNA Traps for Accurate Cross-Linking with Cysteine Residues in DNA–Protein Complexes Using Mismatch Repair Protein MutS as a Model. Molecules, 2022, 27(8), 2438. doi: 10.3390/molecules27082438
- Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, 2021, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
- Kleinpenning, F.; Steigenberger, B.; Wu, W.; Heck, A.J.R. Fishing for newly synthesized proteins with phosphonate-handles. Nature Communications, 2020, 11, 3244. doi: 10.1038/s41467-020-17010-0
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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