叠氮基丁酸 NHS 酯 (Azidobutyric acid NHS ester)

目录号 数量 价格 提前通知时间
53720 50 mg $110 现货
63720 100 mg $210 现货
73720 1 g $950 现货
83720 5 g 请查询 现货
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使用该试剂将蛋白质和多肽转化为点击化学反应形式。

虽然点击化学涉及末端炔烃和叠氮化物之间的反应,但叠氮化物和炔烃在自然界中都非常罕见。然而,有试剂可以将这些片段连接到生物分子上普遍存在的氨基上。这种叠氮-NHS 酯被用于将蛋白质、多肽、氨基-DNA 和其他胺转化为点击化学反应性叠氮化物。

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外观: 无色固体
质谱 M+ 增量: 111.0
分子量: 226.19
CAS 编号: 943858-70-6
分子式: C8H10N4O4
IUPAC 名称: Butanoic acid, 4-​azido-​, 2,​5-​dioxo-​1-​pyrrolidinyl ester
溶解度:
质量控制: NMR 1H (95%), HPLC
储存条件: 储存:收到后在 -20°C 下可保存 12 个月。运输:室温下最多可保存 3 周。干燥。
安全数据表(MSDS): 下载
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产品引用

  1. Osuofa, J.; Husson, S.M. Preparation of Protein A Membranes Using Propargyl Methacrylate-Based Copolymers and Copper-Catalyzed Alkyne–Azide Click Chemistry. Polymers, 2024, 16(2), 239. doi: 10.3390/polym16020239
  2. Skardžiūtė, K.; Kvederavičiūtė, K.; Pečiulienė, I.; Narmontė, M.; Gibas, P.; Ličytė, J.; Klimašauskas, S.; Kriukienė, E. One-pot trimodal mapping of unmethylated, hydroxymethylated, and open chromatin sites unveils distinctive 5hmC roles at dynamic chromatin loci. Cell Chemical Biology, 2024, 31(3), 607-621.e9. doi: 10.1016/j.chembiol.2023.12.003
  3. Afting, C.; Walther, T.; Drozdowski, O. M.; Schlagheck, C.; Schwarz, U. S.; Wittbrodt, J.; Göpfrich, K. DNA Microbeads for Spatio-Temporally Controlled Morphogen Release within Organoids. Nat. Nanotechnol., 2024, 1-9. doi: 10.1038/s41565-024-01779-y
  4. Sim, J.; Li, M.; Park, K. M.; Kim, K. Identification of Mitochondrial Proteins Associated with Cyanine 5 Using a Combination of Affinity-Based Photocrosslinking with Bio-Orthogonal Supramolecular Latching. J. Porphyrins Phthalocyanines, 2023, 27(07n10), 1148–1155. doi: 10.1142/S108842462350058X
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