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LumiCell CDr20 Microglia Stain

目录号 数量 价格 提前通知时间
3570-50ug 50 ug $50 现货
3570-500ug 500 ug $350 现货
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CDr20 (Cell Designation red 20) is a high-performance fluorogenic chemical probe for labeling microglia in both cell cultures and live brains. CDr20 is a substrate of microglia-specific UDP-glucuronosyltransferase Ugt1a7c. The glucuronidation of CDr20 by Ugt1a7c produces bright red fluorescence in microglial cells coinciding with the expression of markers P2ry12, Csf1r, Cx3cr1, and Iba-1 [1].

CDr20 could be a valuable tool for identifying and visualizing microglia in neural disorder studies both in vitro and in vivo and for CDr20-based fluorescent-activated microglial cell sorting (FACS).

[1] Kim B. et al. Visualizing Microglia with a Fluorescence Turn-On Ugt1a7c Substrate. Angew. Chem. Int. Ed. Engl. 2019. 58(24). 7972-7976.

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Non-functionalized Сyanine5.5 dye derivative with good solubility in organic solvents and bright fluorescence in the far-red spectrum range.

General properties

Appearance: greenish black crystals
Molecular weight: 354.17
CAS number: 1201643-01-7
Molecular formula: C19H17BF2N2O2
Solubility: DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表(MSDS): 下载
产品规格

Spectral properties

Excitation/absorption maximum, nm: 562
ε, L⋅mol−1⋅cm−1: 97500
Emission maximum, nm: 581
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