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Cyanine7.5 azide

目录号 数量 价格 提前通知时间
16030 100 uL, 10 mM/DMSO –   现货
36030 500 uL, 10 mM/DMSO $199 现货
46030 1 mL, 10 mM/DMSO $495 现货
A6030 1 mg –   现货
B6030 5 mg $199 现货
C6030 10 mg $297 现货
D6030 25 mg $495 现货
E6030 50 mg $895 现货
F6030 100 mg $1490 现货
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Cyanine7.5 is a NIR dye with long-wave infrared fluorescence. This derivative is azide for click chemistry.

Can be used for the construction of various labeled biomolecules containing Cyanine7.5, near-infrared fluorescent dye, and an improved analog of Cy7.5®. These conjugates can take advantage of NIR tissue transparency when used for in vivo imaging. This fluorophore is also useful for other fluorescent applications, especially requiring low fluorescent background.

Azide is available as a DMSO solution, ready for general click chemistry labeling protocol, or in solid form for custom labeling applications.

Structure features a rigid bridged polymethine chain to increase quantum yield by 20%, allowing for a brighter signal.

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Cyanine3 azide

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General properties

Appearance: green powder / solution
Molecular weight: 767.44
CAS number: 1628790-36-2; 1628897-78-8 (without anion)
Molecular formula: C48H55ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
安全数据表(MSDS): 下载
产品规格

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

产品引用

  1. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
  2. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
  3. Pearce, H.A.; Qian, H.; Connell, T.U.; Huang, D.; Gottstein, C.; Donnelly, P.S.; Peter, K.; Gregorevic, P.; Hagemeyer, C.E. Site-specific glycation and chemo-enzymatic antibody sortagging for the retargeting of rAAV6 to inflamed endothelium. Molecular Therapy - Methods & Clinical Development, 2019, 14, 261–269. doi: 10.1016/j.omtm.2019.07.003
  4. Kong, J.-N.; Zhu, Z.; Itokazu, Y.; Wang, G.; Dinkins, M.B.; Zhong, L.; Lin, H.-P.; Elsherbini, A.; Leanhart, S.; Jiang, X.; Qin, H.; Zhi, W.; Spassieva, S.D.; Bieberich, E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 2018, 59(3), 488–506. doi: 10.1194/jlr.M081877
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