EdU（5-乙炔基-2'-脱氧尿苷）

Alkynes Cell proliferation Click chemistry

目录号	数量	价格	提前通知时间
A0540	5 mg	–	现货
10540	100 mg	$120	现货
20540	250 mg	$195	现货
30540	500 mg	$345	现货
40540	1 g	$590	现货
60540	5 g	请查询	现货

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EdU（5-乙炔基-2’-脱氧尿苷）是一种核苷，是胸苷的类似物，带有乙炔基。这种核苷可充当细胞 DNA 复制器的底物。 EdU 掺入后，含有乙炔基的 DNA可以通过点击化学反应与各种叠氮化染料连接。荧光 DNA 可以通过显微镜检测，或者通过 FACS 进行分细胞选。

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外观:
分子量:	252.22
CAS 编号:	61135-33-9
分子式:	C₁₁H₁₂N₂O₅
溶解度:
质量控制:
储存条件:
安全数据表（MSDS）:	下载
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产品引用

Minutti, C.M.; Piot, C.; Pereira da Costa, M.; Chakravarty, P.; Rogers, N.; Huerga Encabo, H.; Cardoso, A.; Loong, J.; Bessou, G.; Mionnet, C.; Langhorne, J.; Bonnet, D.; Dalod, M.; Tomasello, E.; Reis e Sousa, C. Distinct ontogenetic lineages dictate cDC2 heterogeneity. Nature Immunology, 2024, 25, 448–461. doi: 10.1038/s41590-024-01745-9
Dopeso, H.; Rodrigues, P.; Cartón-García, F.; Macaya, I.; Bilic, J.; Anguita, E.; Jing, L.; Brotons, B.; Vivancos, N.; Beà, L.; Sánchez-Martín, M.; Landolfi, S.; Hernandez-Losa, J.; Ramon y Cajal, S.; Nieto, R.; Vicario, M.; Farre, R.; Schwartz Jr, S.; van Ijzendoorn, S.C.D.; Kobayashi, K.; Martinez-Barriocanal, Á.; Arango, D. RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis. iScience, 2024, 27(4), 109400. doi: 10.1016/j.isci.2024.109400
Alruwaili, M.M.; Zonneville, J.; Naranjo, M.N.; Serio, H.; Melendy, T.; Straubinger, R.M.; Gillard, B.; Foster, B.A.; Rajan, P.; Attwood, K.; Chatley, S.; Iyer, R.; Fountzilas, C.; Bakin, A.V. A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers. Cell Reports Medicine, 2024, 5(3), 101434. doi: 10.1016/j.xcrm.2024.101434
Swan, J.; Szabó, Z.; Peters, J.; Kummu, O.; Kemppi, A.; Rahtu-Korpela, L.; Konzack, A.; Hakkola, J.; Pasternack, A.; Ritvos, O.; Kerkelä, R.; Magga, J. Inhibition of activin receptor 2 signalling ameliorates metabolic dysfunction–associated steatotic liver disease in western diet/L-NAME induced cardiometabolic disease. Biomedicine & Pharmacotherapy, 2024, 175, 116683. doi: 10.1016/j.biopha.2024.116683