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FAM DBCO, 6-isomer

FAM（荧光素）环炔烃 Copper-free click chemistry

目录号	数量	价格	提前通知时间
151F0	1 mg	$110	现货
251F0	5 mg	$160	现货
451F0	25 mg	$260	现货
551F0	50 mg	$370	现货
651F0	100 mg	$525	现货

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Fluorescein (FAM) is one of the oldest yet well-known fluorescent dyes. This derivative of FAM contains the cyclooctyne group (dibenzocyclooctyne, DBCO or ADIBO). Pure 6-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction or SPAAC).

FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. Fluorescein can be detected using a variety of different instruments.

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BDP® 581/591 hydrazide

BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.

AF 343（香豆素）-X-NHS 酯 (AF 343 (Coumarin)-X-NHS ester)

AF 343（香豆素）是一种蓝光发射染料，可用作荧光素 (FAM) 的 FRET 供体。该结构的特点是香豆素 343 荧光团和官能团之间有一个连接体。它提供了更好的溶解性以及荧光团和官能团之间的空间分离。

BDP® TMR NHS 酯

BDP TMR 的胺基反应活性 NHS 酯，明亮的硼二吡咯亚甲基染料，可用于 TAMRA 通道，特别适用于荧光偏振测定。

General properties

Appearance:	orange solid
Molecular weight:	676.71
Molecular formula:	C₄₂H₃₂N₂O₇
Solubility:	good in DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
安全数据表（MSDS）:	下载
	产品规格

Spectral properties

Excitation/absorption maximum, nm:	492
ε, L⋅mol⁻¹⋅cm⁻¹:	74000
Emission maximum, nm:	517
Fluorescence quantum yield:	0.93

产品引用

Kaneda, K.; Takeuchi, Y.; Yamanaka, K.; Hasebe, F.; Maruyama, C.; Hamano, Y. Cell-penetrating activity of a short-chain ε-poly-l-α-lysine. Journal of Bioscience and Bioengineering, 2024, 138(3), 249-253. doi: 10.1016/j.jbiosc.2024.06.006
Wu, F.; Ren, Y.; Lv, W.; Liu, X.; Wang, X.; Wang, C.; Cao, Z.; Liu, J.; Wei, J.; Pang, Y. Generating dual structurally and functionally skin-mimicking hydrogels by crosslinking cell-membrane compartments. Nature Communications, 2024, 15(1), 802. doi: 10.1038/s41467-024-45006-7
Jaiswal, M.; Tran, T. T.; Guo, J.; Zhou, M.; Kundu, S.; Guo, Z.; Fanucci, G. E. Spin-Labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells. Appl Magn Reson, 2023. doi: 10.1007/s00723-023-01624-w
Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425

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Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.