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FAM DBCO, 6-isomer

FAM（荧光素）环炔烃 Copper-free click chemistry

目录号	数量	价格	提前通知时间
151F0	1 mg	$110	现货
251F0	5 mg	$160	现货
451F0	25 mg	$260	现货
551F0	50 mg	$370	现货
651F0	100 mg	$525	现货

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Fluorescein (FAM) is one of the oldest yet well-known fluorescent dyes. This derivative of FAM contains the cyclooctyne group (dibenzocyclooctyne, DBCO or ADIBO). Pure 6-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction or SPAAC).

FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. Fluorescein can be detected using a variety of different instruments.

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AF 488 DBCO

含有绿色荧光团 AF 488的二苯并环辛炔（DBCO、ADIBO），可用于标记活细胞、整个生物体和无生命样品内的叠氮化物生物分子。纯5-异构体。

Cyanine5叠氮化物

Cyanine5 叠氮化物是一种用 Cyanine5（一种流行的荧光染料）进行点击化学标记的试剂。

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Cyanine5 tetrazine

Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.

General properties

Appearance:	orange solid
Molecular weight:	676.71
Molecular formula:	C₄₂H₃₂N₂O₇
Solubility:	good in DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
安全数据表（MSDS）:	下载
	产品规格

Spectral properties

Excitation/absorption maximum, nm:	492
ε, L⋅mol⁻¹⋅cm⁻¹:	74000
Emission maximum, nm:	517
Fluorescence quantum yield:	0.93

产品引用

Kaneda, K.; Takeuchi, Y.; Yamanaka, K.; Hasebe, F.; Maruyama, C.; Hamano, Y. Cell-penetrating activity of a short-chain ε-poly-l-α-lysine. Journal of Bioscience and Bioengineering, 2024, 138(3), 249-253. doi: 10.1016/j.jbiosc.2024.06.006
Wu, F.; Ren, Y.; Lv, W.; Liu, X.; Wang, X.; Wang, C.; Cao, Z.; Liu, J.; Wei, J.; Pang, Y. Generating dual structurally and functionally skin-mimicking hydrogels by crosslinking cell-membrane compartments. Nature Communications, 2024, 15(1), 802. doi: 10.1038/s41467-024-45006-7
Jaiswal, M.; Tran, T. T.; Guo, J.; Zhou, M.; Kundu, S.; Guo, Z.; Fanucci, G. E. Spin-Labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells. Appl Magn Reson, 2023. doi: 10.1007/s00723-023-01624-w
Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425

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Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.