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FAM DBCO, 6-isomer

FAM（荧光素）环炔烃无铜点击化学

目录号	数量	价格	提前通知时间
151F0	1 mg	$110	现货
251F0	5 mg	$160	现货
451F0	25 mg	$260	现货
551F0	50 mg	$370	现货
651F0	100 mg	$525	现货

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Fluorescein (FAM) is one of the oldest yet well-known fluorescent dyes. This derivative of FAM contains the cyclooctyne group (dibenzocyclooctyne, DBCO or ADIBO). Pure 6-isomer. DBCO reacts quickly and efficiently with azides by simply mixing the components without the need for a copper catalyst (so-called sterically promoted cycloaddition reaction or SPAAC).

FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. Fluorescein can be detected using a variety of different instruments.

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FAM 炔烃，5-异构体 (FAM alkyne, 5-isomer)

FAM 炔烃，5-异构体，一种荧光素染料的炔烃衍生物，用于点击化学。

DiO，亲脂性示踪剂 (DiO, lipophilic tracer)

用于膜标记和细胞示踪的绿色荧光亲脂染料。

AF 594 NHS酯 (AF 594 NHS ester)

AF 594 染料的红色荧光 NHS-酯，用于标记蛋白质、肽、抗体和任何含有 -NH2 基团的分子。纯5-异构体

General properties

Appearance:	orange solid
Molecular weight:	676.71
Molecular formula:	C₄₂H₃₂N₂O₇
Solubility:	good in DMF, DMSO
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
安全数据表（MSDS）:	下载
	产品规格

Spectral properties

Excitation/absorption maximum, nm:	492
ε, L⋅mol⁻¹⋅cm⁻¹:	74000
Emission maximum, nm:	517
Fluorescence quantum yield:	0.93

产品引用

Kaneda, K.; Takeuchi, Y.; Yamanaka, K.; Hasebe, F.; Maruyama, C.; Hamano, Y. Cell-penetrating activity of a short-chain ε-poly-l-α-lysine. Journal of Bioscience and Bioengineering, 2024, 138(3), 249-253. doi: 10.1016/j.jbiosc.2024.06.006
Wu, F.; Ren, Y.; Lv, W.; Liu, X.; Wang, X.; Wang, C.; Cao, Z.; Liu, J.; Wei, J.; Pang, Y. Generating dual structurally and functionally skin-mimicking hydrogels by crosslinking cell-membrane compartments. Nature Communications, 2024, 15(1), 802. doi: 10.1038/s41467-024-45006-7
Jaiswal, M.; Tran, T. T.; Guo, J.; Zhou, M.; Kundu, S.; Guo, Z.; Fanucci, G. E. Spin-Labeling Insights into How Chemical Fixation Impacts Glycan Organization on Cells. Appl Magn Reson, 2023. doi: 10.1007/s00723-023-01624-w
Sapozhnikova, K. A.; Gulyak, E. L.; Misyurin, V. A.; Simonova, M. A.; Ryabukhina, E. V.; Alexeeva, A. V.; Tikhonova, N. A.; Lyzhko, N. A.; Popova, G. P.; Misyurin, A. V.; Ustinov, A. V.; Korshun, V. A.; Alferova, V. A.; Ryazantsev, D. Y.; Brylev, V. A. Branched Linkers for Site-Specific Fluorescent Labeling of Antibodies. Molecules, 2023, 28(1), 425. doi: 10.3390/molecules28010425

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Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.