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ICG maleimide

目录号 数量 价格 提前通知时间
28080 5 mg $198 21 天
48080 25 mg $598 21 天
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Indocyanine Green (ICG, IC Green, Foxgreen) is a negatively charged tricarbocyanine dye widely used for imaging and flow cytometry due to its low toxicity and near-infrared fluorescence emission.

ICG has an absorption maximum at 787 nm with slight absorption in the visible range and a fluorescence emission maximum at 819 nm. The minimal light scattering and low autofluorescence in this spectral range result in a significantly reduced background and improved signal-to-noise ratios, thereby enhancing detection sensitivity.

ICG maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach ICG fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or with another appropriate reductant prior to the labeling.

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General properties

Appearance: dark green powder
Molecular weight: 853.08
CAS number: 2143933-81-5
Molecular formula: C51H56N4O6S
Solubility: DMSO (with sonication)
Quality control: NMR 1H and HPLC-MS (90+%)
Storage conditions: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表(MSDS): 下载
产品规格

Spectral properties

Excitation/absorption maximum, nm: 787
ε, L⋅mol−1⋅cm−1: 232000
Emission maximum, nm: 819
Fluorescence quantum yield: 0.09
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