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Perylene azide

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目录号 数量 价格 提前通知时间
A5530 1 mg 请查询 现货 (2 pcs)
B5530 5 mg 请查询 现货 (2 pcs)
C5530 10 mg 请查询 现货 (3 pcs)
D5530 25 mg 请查询 现货 (2 pcs)
E5530 50 mg 请查询 现货 (2 pcs)
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This product will be discontinued soon. We may still have some material in stock (please see availability above).

Perylene is a bright and extremely photostable fluorescent polycyclic aromatic hydrocarbon (PAH) label with quantum yield approaching quantitative.

Due to low life time of fluorescence, this probe does not form excimers.

Perylene labeling of biomolecules is used to be difficult and tedious because of low solubility of perylene, and low availability of activated derivatives. However, labeling via Click Chemistry with this perylene azide is nearly as easy, as with other dyes. Labeling peptide, DNA, protein with this polyaromatic hydrocarbon has never been so simple yet.

To increase hydrophilicity, and facilitate labeling, this PAH azide contains hydrophilic triethyleneglycol linker.

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Cyanine7 alkyne

Cyanine7 alkyne is a near infrared (NIR) dye alkyne for click chemistry.
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ROX alkyne, 5-isomer

An alkyne derivative of bright red-emitting dye ROX (Rhodamine X, Rhodamine 101) for copper-catalyzed click chemistry bioconjugation. Pure 5-isomer.

General properties

Appearance: orange-yellow solid
Molecular weight: 452.50
CAS number: 1807503-81-6
Molecular formula: C27H24N4O3
IUPAC name: 3-(8-Azido-3,6-trioxaoctylaminocarbonyl)perylene
Solubility: good in dichloromethane and chloroform, moderate in DMSO, DMF, and acetonitrile
Quality control: NMR 1H (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
安全数据表(MSDS): 下载
产品规格

Spectral properties

Excitation/absorption maximum, nm: 435; 408; 252
ε, L⋅mol−1⋅cm−1: 36000
Emission maximum, nm: 439; 467
Fluorescence quantum yield: 1.0

产品引用

  1. Bednarczyk, M.; Peters, J.K.; Kasprzyk, R.; Starek, J.; Warminski, M.; Spiewla, T.; Mugridge, J.S.; Gross, J.D.; Jemielity, J.; Kowalska, J. Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9. ACS Chemical Biology, 2022, 17(6), 1460-1471. doi: 10.1021/acschembio.2c00049
  2. Epanchintseva, A. V.; Gorbunova, E. A.; Ryabchikova, E. I.; Pyshnaya, I. A.; Pyshnyi, D. V. Effect of Fluorescent Labels on DNA Affinity for Gold Nanoparticles. Nanomaterials, 2021, 11(5), 1178. doi: 10.3390/nano11051178
  3. Taskova, M.; Astakhova, K. Fluorescent Oligonucleotides with Bis(prop-2-yn-1-yloxy)butane-1,3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids. Bioconjugate Chemistry, 2019, 30(12), 3007–3012. doi: 10.1021/acs.bioconjchem.9b00746
  4. Westergaard Mulberg, M.; Taskova, M.; Thomsen, R.P.; Okholm, A.H.; Kjems, J.; Astakhova, K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem, 2017, 18(16), 1599–1603. doi: 10.1002/cbic.201700125
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