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sulfo-Cyanine5.5 amine

目录号 数量 价格 提前通知时间
173C0 1 mg $125 现货
273C0 5 mg $285 现货
473C0 25 mg $680 现货
573C0 50 mg $1260 现货
673C0 100 mg $1990 现货
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sulfo-Cyanine5.5 is a water-soluble cyanine dye for far red / NIR applications such as in vivo imaging. The dye possesses four sulfonate groups, rendering it highly hydrophilic and water-soluble. As well as other cyanines, sulfo-Cyanine5.5 has an outstanding extinction coefficient that makes it a bright fluorescent label for the far-red region.

This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. The aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc.) and used in enzymatic transamination labeling.

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磺基-菁5四嗪 (sulfo-Cyanine5 tetrazine )

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6-Carboxy-H2DCFDA (6-carboxy-2',7'-dichlorodihydrofluorescein)

A reagent for detecting reactive oxygen species (ROS) in living cells. This carboxylated H2DCFDA analog has two additional negative charges that impede its leakage out of the cell.

General properties

Appearance: dark blue solid
Molecular weight: 1077.41
CAS number: 2183440-46-0
Molecular formula: C46H54K2N4O13S4
IUPAC name: (E)-4-[(2E,4E)-5-{5-[6-(6-Aminohexylamino)-6-oxohexyl]-3,3-dimethyl-10,12-bis(oxysulfonyl)-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid dipotassium salt
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
安全数据表(MSDS): 下载
产品规格

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

产品引用

  1. Cheon, S.Y.; Park, J.S.; Lee, Y.; Lee, C.; Jeon, H.; Lee, D.; Kim, S.H.; Lim, S.G.; Koo, H. Injectable and Self‐Curing Single‐Component Hydrogel for Stem Cell Encapsulation and In Vivo Bone Regeneration. Advanced Science, 2024, 11(16), 2304861. doi: 10.1002/advs.202304861
  2. Gao, W.; He, J.; Chen, L.; Meng, X.; Ma, Y.; Cheng, L.; Tu, K.; Gao, X.; Liu, C.; Zhang, M.; Fan, K.; Pang, D.-W.; Yan, X. Deciphering the Catalytic Mechanism of Superoxide Dismutase Activity of Carbon Dot Nanozyme. Nature Communications, 2023, 14(1), 160. doi: 10.1038/s41467-023-35828-2
  3. Shevchuk, A. I.; Svinko, V. O.; Smirnov, A. N.; Solovyeva, E. V. SERS Study of Cyanine Dyes: Optimization of Metal Core and Molecular Label Choice for Plasmonic Nanotags. Dyes and Pigments, 2023, 216, 111329. doi: 10.1016/j.dyepig.2023.111329.
  4. Wang, D.; Li, Y.; Deng, X.; Torre, M.; Zhang, Z.; Li, X.; Zhang, W.; Cullion, K.; Kohane, D. S.; Weldon, C. B. An Aptamer-Based Depot System for Sustained Release of Small Molecule Therapeutics. Nature Communications, 2023, 14(1), 2444. doi: 10.1038/s41467-023-37002-0
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