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TFA-amino modifier CPG 500

目录号 数量 价格 提前通知时间
11860 100 mg $60 现货
21860 250 mg $120 现货
31860 500 mg $230 现货
41860 1 g $380 现货
51860 5 g $1450 5 天
61860 10 g $2465 现货
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This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.

The reagent is based on hydroxyprolinol core - a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.

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Phosphate CPG 1000 solid support

Phosphate modifier CPG for the solid phase synthesis of long (up to 120mer) oligonucleotides containing 3 prime phosphate modification.

六乙二醇亚磷酰胺 (Hexaethylene glycol phosphoramidite)

间隔基亚磷酰胺 18(六乙二醇亚酰胺)为寡核苷酸合成提供一个长的亲水性连接基。

FAM phosphoramidite, 5-isomer

Single isomer 5-FAM phosphoramidite for the synthesis of modified oligonucleotides.

General properties

Appearance: off-white beads
Quality control: NMR 1H and HPLC-MS (95%) of bound reagent, loading measurement
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表(MSDS): 下载
产品规格

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 50−80
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases

产品引用

  1. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
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