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Vacuolin-1

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3255-25mg 25 mg $200 现货
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Vacuolin-1 is a triazine-based small chemical, a specific inhibitor of Ca2+–dependent lysosomal exocytosis. The inhibitor penetrates the cell, blocking the fusion of lysosomes with the plasma membrane. Vacuolin-1 does not affect other membrane-bound organelles and endocytic or secretory traffic. The inhibitor is widely used in studies on the release of lysosomal content and the modulation of autophagy.

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General properties

Appearance: white powder
Molecular weight: 577.43
CAS number: 351986-85-1
Molecular formula: C26H24IN7O
IUPAC name: 3-Iodobenzaldehyde [4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
Solubility: soluble in DMSO
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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