炔基马来酰亚胺 (Alkyne maleimide)

目录号 数量 价格 提前通知时间
41780 25 mg $95 现货
51780 50 mg $175 现货
61780 100 mg $200 现货
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炔基马来酰亚胺是一种双功能连接试剂,可将末端炔基连接至各种含巯基的分子上,如含有半胱氨酸残基的蛋白质。然后,通过铜催化的点击化学反应,炔基可以与各种叠氮化物结合。

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外观:
质谱 M+ 增量: 234.1
分子量: 234.25
分子式: C12H14N2O3
溶解度:
质量控制:
储存条件:
安全数据表(MSDS): 下载
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产品引用

  1. Hulce, K.R.; Jaishankar, P.; Lee, G.M.; Bohn, M.-F.; Connelly, E.J.; Wucherer, K.; Ongpipattanakul, C.; Volk, R.F.; Chuo, S.-W.; Arkin, M.R.; Renslo, A.R.; Craik, C.S. Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine. Cell Chemical Biology, 2022, 29(5), 785-798.e19. doi: 10.1016/j.chembiol.2022.03.007
  2. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, 2021, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
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