此页面上的某些内容不提供英文版本，默认显示为当前可用的语言。

Melatonin-d3

目录号 数量 价格 提前通知时间
4287-500ug 0.50 mg $44 12 天
4287-5mg 5.0 mg $238 7 天
批量询价
Found better price? Let us know and we will propose the way forward!

Melatonin-d3 is a deuterium-labeled stable isotopic analogue of the main pineal gland hormone, used as standards in NMR spectroscopy and mass spectrometry.

Melatonin takes part in the regulation of sleep, the activity of the endocrine system, circulatory and immune systems, and its pronounced antioxidant effect is also known. Replacing hydrogen atoms with its stable isotope, deuterium, allows absorption, distribution and metabolism to be determined in in vivo experiments [1]. The use of melatonin-d3 as a standard for mass spectrometry made it possible to accurately determine the melatonin content in biological fluids, such as blood plasma [2], urine [1], breast milk [3].

[1] Leone R.M. and Silman R.E. Melatonin can be differentially metabolized in the rat to produce N-acetylserotonin in addition to 6-hydroxy-melatonin. Endocrinology. 1984. 114(5). P.1825-1832.

[2] Zhao H., et al. A novel LC-MS/MS assay for the simultaneous determination of melatonin and its two major metabolites, 6-hydroxymelatonin and 6-sulfatoxymelatonin in dog plasma: Application to a pharmacokinetic study. J Pharm Biomed Anal. 2016. 117. P. 390-397.

[3] Jin W., et al. High-throughput quantitation of trace level melatonin in human milk by on-line enrichment liquid chromatography-tandem mass spectrometry. Anal Chim Acta. 2021. 1176:338764.
以ChemDraw格式下载

General properties

Appearance: gray solid
Molecular weight: 235.30
CAS number: 90735-69-6
Molecular formula: C13H13D3N2O2
IUPAC name: N-(2-(5-methoxy-1H-indol-3-yl)ethyl)acetamide-2,2,2-d3
Solubility: Acetonitrile, DMSO
Quality control: NMR 1H and HPLC-MS (95+ %, D: 98+ %)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
安全数据表（MSDS）: 下载
产品规格
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
您的商品已添加. 查看您的 购物车 或者 继续结账
商品数量不正确.