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Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)

目录号 数量 价格 提前通知时间
3662-5mg 5 mg
$129.00
现货
3662-25mg 25 mg
$240.00
现货
3662-100mg 100 mg
$630.00
现货
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Tetraacetylated N-azidoacetylglucosamine (Ac4GlcNAz) is an azide-labeled monosaccharide widely used to study glycoproteins through in vivo metabolic incorporation followed by chemoselective ligation.

Ac4GlcNAz is a synthetic sugar that can penetrate cells, where it is recruited into natural metabolic pathways and displaces the endogenous N-acetylglucosamine (GlcNAc).

This results in the formation of glycoproteins bearing azide groups, which can be detected by click chemistry—a Cu(I)-catalyzed (CuAAC) or copper-free (SPAAC) reaction—using fluorescent alkynes/cycloalkynes or biotin-alkyne.

Concentrations of 25–75 μM are typically used for cell labeling; this range provides a convenient starting point for developing an experimental protocol.

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General properties

Appearance: white solid
Molecular weight: 430.37
CAS number: 98924-81-3
Molecular formula: C16H22N4O10
Solubility: DMSO, DMF, DCM, THF, Chloroform
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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